A group of medical researchers, engineers, and computer scientists from various institutions around the United States discovered that machine learning technology can assist clinicians in predicting which individuals are in danger of acquiring COPD. The researchers used patient spirogram data to construct a deep-learning network to predict the development of COPD in their study, which was published in the journal Nature Genetics. COPD is the world’s third leading cause of death. The word refers to a wide range of obstructive lung diseases, including asthma, bronchitis, and emphysema. A previous study has indicated that the sooner COPD is treated, the sooner medicines can be used to reduce its progression. As a result, medical researchers have worked hard to develop new methods for identifying people who are at risk.
The study team employed machine learning for the task in this latest endeavor.
The researchers constructed a deep convolutional neural network to distinguish between persons who have COPD and those who do not. The system was taught using data from patient medical records, potential diagnosis classification systems, and spirograms. Patients are given spirometry, which involves blowing into a tube-like device that is attached to a machine that calculates lung strength.
Once the system could distinguish between healthy and COPD lungs, the scientists incorporated liability score data accumulated over many years to assist detect early COPD in patients.
They then tested the method on data from 325,000 UK Biobank patients, which included spirograms. They also gave risk data from participants in a number of other healthcare initiatives. They discovered that they could teach the algorithm to recognize early indicators of COPD in patients.
The team ends by saying that by giving it spirogram data, their method could soon be used to screen patients for COPD. They also mention that it could be used in new research efforts to better understand how the disease begins in the lungs and why it sometimes advances so swiftly.
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