Diet and healthy aging: insights from a 15-year Swedish study
A large 15-year longitudinal study from Sweden underscores the critical role of healthy dietary patterns in reducing multimorbidity in older adults. Researchers assessed how adherence to the Mediterranean diet (AMED), MIND diet, and Alternate Healthy Eating Index (AHEI) influenced long-term health outcomes. Findings reveal that individuals following these diets experienced a slower increase in chronic disease burden, especially in cardiovascular multimorbidity and neuropsychiatric conditions.
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Conversely, high adherence to a pro-inflammatory diet (EDII) was associated with faster disease accumulation, highlighting the impact of dietary choices on diet and healthy aging. The study emphasizes that focusing on overall dietary patterns, rather than individual foods, provides a clearer picture of long-term health benefits.
Anti-inflammatory nutrition and organ-specific benefits
Participants with the highest adherence to the MIND and AHEI diets demonstrated a remarkable clinical difference, accumulating approximately two fewer chronic conditions over 15 years compared to those with the lowest adherence. This gap is clinically significant for geriatric care, as reducing even a single chronic condition can translate into better quality of life, lower hospitalization rates, and decreased healthcare costs. The strongest benefits were observed in cardiovascular multimorbidity and neuropsychiatric conditions, suggesting that anti-inflammatory nutrition plays a key role in protecting both vascular and cognitive health during aging. The nutrient-dense profiles of these diets, rich in fruits, vegetables, whole grains, and omega-3 sources, likely contribute to reducing systemic inflammation and oxidative stress, two major pathways implicated in chronic disease progression.
Interestingly, while the Mediterranean diet (AMED) also exhibited protective effects consistent with previous research, secondary analyses revealed a potential association with a slightly accelerated rate of musculoskeletal multimorbidity. Although the clinical significance of this finding remains uncertain, it highlights that dietary effects may differ across organ systems. Factors such as protein distribution, calcium intake, or interactions with age-related sarcopenia could be influencing these outcomes. For clinicians, this underscores the need for personalized nutrition strategies that take into account individual risk profiles, coexisting conditions, and dietary tolerances in older adults. It also suggests that combining dietary interventions with targeted exercise and musculoskeletal health strategies may optimize outcomes.
Clinical implications for healthcare professionals
For HCPs and nurses, these results provide actionable insights for preventive care and patient education. Dietary counseling for older adults can integrate guidance on adopting healthy dietary patterns such as AHEI and MIND, which have demonstrated the strongest associations with reduced disease burden. Encouraging patients to shift away from pro-inflammatory diets (EDII) can support better outcomes for both cardiovascular and neuropsychiatric health.
In geriatric and primary care settings, these findings also reinforce the value of dietary assessment as part of routine care for community-dwelling older adults. By promoting healthy aging strategies, clinicians can help patients reduce the long-term impact of multimorbidity and maintain functional independence. The study’s robust design, spanning over a decade and incorporating repeated dietary assessments, provides a strong evidence base for integrating nutrition-focused interventions into chronic disease management protocols.
For More Information:
Abbad-Gomez D, Carballo-Casla A, Beridze G, et al. Dietary patterns and accelerated multimorbidity in older adults. Nature Aging (2025). DOI: 10.1038/s43587-025-00929-8 https://www.nature.com/articles/s43587-025-00929-8
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